Bactericidal and bacteriostatic; inhibits protein synthesis after binding with 50S ribosomal subunit of susceptible organisms. Demonstrates cross-resistance to erythromycin-resistant gram-positive strains and resistance to most strains of Enterococcus faecalis and methicillin-resistant Staphylococcus aureus. pneumoniae Adults: Instill 1 drop in affected eye(s) b.i.d., 8 to 12 hours apart for first 2 days; then instill 1 drop in affected eye(s) once daily for next 5 days Mild community-acquired pneumonia Adults: 500 mg P. Oral suspension: 100 mg/5 ml in 15-ml bottles; 200 mg/5 ml in 15-ml, 22.5-ml, and 30-ml bottles Oral suspension (Zmax extended-release): 2-g bottle Powder for injection: 500 mg in 10-ml vials Powder for oral suspension: 100 mg/5 ml, 200 mg/5 ml, 1,000 mg/packet Solution (ophthalmic): 1% in 5-ml bottle filled with 2.5 ml solution Tablets: 250 mg, 500 mg, 600 mg Tablets (Tri-Pak): three 500-mg tablets Tablets (Z-Pak): six 250-mg tablets Bacterial conjunctivitis caused by CDC coryneform group G, H. aureus Adults and adolescents ages 16 and older: 500 mg I. (no more than 500 mg/dose) on day 1, then 5 mg/kg (no more than 250 mg/dose) for 4 more days Community-acquired pneumonia caused by Chlamydia pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Streptococcus pneumoniae, Legionella pneumophila, Moraxella catarrhalis, and S. daily for a total of 7 to 10 days Children ages 6 months to 16 years: 10 mg/kg P. on days 2 through 5 Pharyngitis and tonsillitis Adults: 500 mg P. on day 1, then 250 mg/day for next 4 days, to a total dosage of 1.5 g Children ages 2 and older: 12 mg/kg P. valacyclovir weight gain Azithromycin has relatively broad but shallow antibacterial activity. It inhibits some Gram-positive bacteria, some Gram-negative bacteria, and many atypical bacteria. A strain of gonorrhea reported to be highly resistant to azithromycin was found in the population in 2015. Neisseria gonorrhoeae is normally susceptible to azithromycin, Safety of the medication during breastfeeding is unclear. 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