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    Sometimes premature ejaculation (PE) is a problem in men who also have Erectile Dysfunction (ED). ED is the inability to achieve or maintain an erection that is firm enough for satisfactory sexual intercourse. PE is where a man ejaculates too quickly after the initiation of sexual intercourse. The definition of ‘too quickly’ is not set in stone, it depends very much on the individual and what the man and his partner deem satisfactory. PE may be caused by ED, especially in a man who needs continued penile stimulation to maintain his erection. Both medications cause the effect of lowering of blood pressure. Viagra is a safe treatment for ED, and Priligy is a treatment for PE. Together, the combined effect may be to reduce blood pressure to a low enough level that symptoms such as fainting will occur (known as orthostatic hypotension). This occurs when there is a drop in blood pressure when the person stands up and causes dizziness, lightheadedness and possible fainting. buy flagyl 500mg online As a member of the selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant. Originally created by Eli Lilly pharmaceutical company, dapoxetine was sold to Johnson & Johnson in 2003 and submitted as a New Drug Application to the Food and Drug Administration (FDA) for the treatment of PE in 2004. Different dosage has different impacts on different types of PE. Dapoxetine 60 mg significantly improves the mean intravaginal ejaculation latency time (IELT) compared to that of dapoxetine 30 mg in men with lifelong PE, but there is no difference in men with acquired PE. Dapoxetine, given 1–3 hours before sexual episode, prolongs IELT and increases the sense of control and sexual satisfaction in men of 18 to 64 years of age with PE.

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    January 2009 Anyone with a television probably knows that three prescription medications currently are used to treat erectile dysfunction (ED): sildenafil (VIAGRA), tadalafil (CIALIS) and vardenafil (LEVITRA). These drugs, which belong to the class of drugs called phosphodiesterase-5 inhibitors (PDE5i), are widely used, especially in older men. And because older men are more likely to be concurrently taking other medications, they should be aware of the potential for dangerous interactions when ED drugs are mixed with other prescription drugs. This article deals only with these three approved prescription ED drugs, not the many untested ED products widely advertised on the Internet and elsewhere (see Tables 1, 2, and 3). Sildenafil, tadalafil and vardenafil are drugs that cause the dilation of blood vessels (vasodilators) and this effect can be magnified when they are used with other medications with similar vasodilating effects. It is this vasodilating effect that increases blood flow to the penis causing an erection. Most ED drug interactions, however, result from the fact that these drugs are metabolized by the enzyme CYP3A4 in the intestine and liver. CYP3A4 is the most important enzyme for drug metabolism, and many medications can interact with ED drugs by decreasing or increasing CYP3A4 activity, causing ED drug levels to increase or decrease, respectively. Cialis Tadalafil Side Effects, Interactions, Warning. prednisone emedicine Cialis Tadalafil Side Effects, Interactions, Warning, Dosage & Uses Cialis How it works, uses, side effects - Medical News Today
     
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