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The facts and conclusions presented may have since changed and may no longer be accurate. Questions about personal health should always be referred to a physician or other health care professional. 15, 2010 (Health Day News) -- The commonly used diabetes medication metformin sometimes has such an unpleasant odor that people may stop taking it, experts say. But they recommend that people let their doctors know if the smell of this oral drug is an issue for them, because different formulations -- especially the extended-relief version -- tend to have a milder odor, if any at all, reports a letter in the Feb. "Metformin is an excellent drug, but the immediate-release formulation may have an odor to it. The smell is fishy or like the inside of an inner tube, and in a patient's mind, because it smells like something that has gone bad, they may think the drug isn't good," explained one of the letter's authors, J. 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