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A combination of physiological and psychological factors is believed to impact on ejaculatory latency, and research suggests that serotonin plays a central role. The negative consequences of premature ejaculation are significant they cause: sexual dissatisfaction, personal distress, interpersonal difficulty, low self-esteem, and they may affect partner satisfaction. Priligy (dapoxetine) is the first oral medication approved for "on-demand" premature ejaculation treatment. Priligy is a unique, short-acting, selective serotonin reuptake inhibitor designed to be taken only when needed - one to three hours before sexual intercourse is anticipated - rather than every day. Priligy was originally developed by Janssen, and is specifically indicated for the on-demand premature ejaculation treatment. Priligy is a medication used in the treatment of PE (premature ejaculation). 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