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    Celebrex, a prescription pain medication in the same class as Vioxx, which was pulled from the market in 2004 over cardiovascular concerns, is as safe as over-the-counter (OTC) pain medications. However, you may want to think twice before switching from Advil or Aleve to Celebrex. The somewhat surprising finding is the result of a 10-year study conducted by Pfizer, the maker of Celebrex, involving more than 24,000 people with arthritis who either had heart disease or were at high risk for it. They were given either Celebrex (celecoxib), a drug known as a COX-2 inhibitor, Advil (ibuprofen) or Aleve (naproxen). The latter two are available OTC and are known as NSAIDs (non-steroidal anti-inflammatory drugs). Although the study was funded by Pfizer, the lead author was Steven Nissen, MD, a cardiologist at the Cleveland Clinic, who was one of the first physicians to sounds alarms about links between Vioxx and an increased risk of heart attack and stroke. Published in the New England Journal of Medicine, the study not only found that all 3 medications had similar efficacy, but all had nearly the same rate of heart disease, heart attack or stroke from taking it. CELEBREX is an FDA-approved NSAID (nonsteroidal anti-inflammatory drug) used to treat the signs and symptoms of osteoarthritis (OA) and rheumatoid arthritis (RA), juvenile rheumatoid arthritis in patients 2 years and older, and ankylosing spondylitis; and for the management of acute pain in adults, and for the management of menstrual cramps. Some patients and their doctors prefer brand-name medications. When you and your doctor decide brand-name CELEBREX is right for you, ask your doctor to indicate “DAW”—or the language used in your state—on your prescription and make sure that’s what your pharmacist gives you. The CELEBREX Savings Card allows eligible patients to pay as little as $4 every time they get a 30-day fill of brand-name CELEBREX—and could save up to $1,750 a year. If you have a prescription for brand-name CELEBREX, you can use the card for every fill through December 31, 2019.* *Terms and conditions apply. Yes, for reimbursement when using a nonparticipating pharmacy: Pay for CELEBREX prescription, and mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: CELEBREX Savings Card, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560. Be sure to include a copy of the front of your Savings Card, your name, and mailing address.

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